Oxide of Ethylene. Gaseous chromatography INDRODUO the sterilization process has the purpose to remove or to destroy all the forms of microbiana life for a sterility level segura1.
The sterilization can be made by means of the application of dry heat or humid, agent gaseous, chemical and physical and all the processes must be validados2. The oxide of ethylene (EtO) discovered by Wurtz in 1859, started to be produced commercially in 1921 and from 1962 it was adopted as method of sterilization for materials sensible to calor3. The EtO exerts lethal action through alquilao, in mainly acid nuclicos, hindering the protein synthesis and destroying esporos, bacteria, fungos and vrus4, become a safe method and eficaz5. The use of the fast Bioindicador (third generation) allows time profit and productivity and to prove the efficiency of the sterilization was carried through the validation of the process through the physical, microbiological and chemical qualification. MATERIAL AND METHODS Are about quantitative study of descriptive analysis carried through in the FBM pharmaceutical industry in the city of Anpolis-GO. The results had been express on average DP and DPR% for the Programs Graphpad Instat 3,0 have tested (Turkey Kramer) and Biostat 4,0 has tested (Shapiro Wilk), considering significant p gaseous chromatograph (Young Lin, 6100 series), clipador (Wheaton E-Z Crimper), declipador (Kebby Decapper), fast incubadora (3M), chemical Integrator classroom IV (Browne), face mask 6899-B (3M), standard EtO 5,000 ppm (SOLUTECH) lots 2695/2696, paper surgical degree (Rexan), Automatic pipette (Labmate) 100 L and 500 L, dismissable and vial tip.